Correlation of Diplopia and Quality of Life in Patients with Graves Orbithopathy
Maria Alarcón, MD; Maria Nieves, MD; De Pablo Lucia, MD; Niño Cristina, MD; Rosario Gomez De Liaño, MD;
Jose Fernandez Vigo, MD
Hospital Clínico Universitario San Carlos
Introduction: At least 40% of patients with Graves Orbitopathy (GO) suffer from diplopia which affects severely to their the daily activities. The purpose of the study is to evaluate the single visual field SVF with an objective method and correlate it with the quality of life (QoL) in patients with GO.
Methods: 60 patients with GO were studied measuring clinical activity score, diplopia with a plane method, cover test, maddox rod, ductions and diplopia questionaire. QoL was assesed with de GO-Qol questionnaire.
Results: Data analyze shows good correlation between QoL and area of BVF and perception of diplopia. We didn´t found stadistical differences beetwen active or inactive patients for de visual functioning or the appearance in the QoL questionnaire.
Discussion: The difference in QoL between active and inactive patients didn´t achieved the statistical significance probably due to the small number of active patients in our study, compared to other studies published in the literature. Constant diplopia and BSVF are well correlated with QoL.
Conclusion: GO- QoL can affeted by be several factors, for that reason it is interesting studying which of them are of more importance in order to plan treatment in these patients.
References: 1. Terwee CB, Gerding MN, Dekker FW, et al. Development of a disease specific quality of life questionnaire for patients with Graves’ Ophthalmopathy: the GO-QoL. Br J Ophthalmol 1998;82(7):772-9.
- Fayers T, Dolman PJ. Validity and reliability of the TED-QoL: a new three-item questionnaire to assess quality of life in thyroid eye disease. Br J Ophthalmol 2011;95(12):1670-974.
- Wiersinga WM, Perros P, Kahaly GJ, et al. Clinical assessment of patients with Graves’ Orbitopathy: the European Group on Graves’ Orbitopathy recommendations to generalists, specialists and clinical researchers. Eur J Endocrinol 2006;155:387-9.
- Park JJ, Sullivan TJ, Mortimer RH, et al. Assessing quality of life in Australian patients with Graves’ Ophthalmopathy. Br J Ophthalmol 2004;88:75-8.
- Choi YJ, Lim HT, Lee SJ, Yoon JS. Assessing Graves’ Ophthalmopathy-specific quality of life in Korean patients. Eye 2012;26:544-51.
- Ponto KA, Hommel G, Pitz S, et al. Quality of life in German Graves’ Orbitopathy population. Am J Ophthalmol 2011;152:483-90.
- Quality of life improves after strabismus surgery in patients with Graves’ orbitopathy.Hinke Marijke Jellema, Elly Merckel-Timmer, Roel Kloos, Peerooz Saeed and Maarten P Mourits. Eur J Endocrinol. 2014;170(5):785-9