Electroretinography Using the RetEval™ ERG System in Healthy Children
Katie M. Keck; Charles S. Atkinson, MD
Children’s Mercy Hospital
Kansas City, MO
Introduction: Recent innovation has led to the development of the hand-held RetEval™ ERG system (LKC Technologies, Gaithersburg, MD USA) which utilizes skin electrodes and can be performed without anesthesia. The purpose of this study is to determine reference range values for electroretinography (ERG) in healthy children using the RetEval™ ERG system.
Methods: The RetEval ERG system was used to record full ERGs in 20 healthy, awake subjects (age 4-17) using skin electrodes. A modified ISCEV 5 step protocol was utilized.
Results: Data was obtained from 38 eyes of 20 healthy subjects. The results of the ERG recordings, expressed as median values (range), are as follows:
Isolated rod amplitude: 50.2uV (15.3 – 102.0)
Mixed rod/cone b-wave amplitude: 67.1uV (43.8 – 125.0)
Mixed rod/cone b-wave implicit time: 45.7ms (32.5 – 69.1)
Oscillatory potential: 53.5uV (22.0 – 114.0)
Isolated cone amplitude: 35.8uV (18.2 – 192)
Flicker amplitude: 27.9.2uV (13.6 – 105)
Flicker implicit time: 24.4ms (23.3 – 28.3)
Discussion: This study provides data that allows calculation of reference values for full ERG using the RetEval™ system in healthy children. The RetEval™ ERG system was well tolerated by all ages and could eliminate the need for ERG under anesthesia in children.
Conclusion: RetEval is useful for ERG in children.
References: McCulloch DL, Marmor MF, Brigell MG, et al. ISCEV Standard for full-field clinical electroretinography (2015 update). Doc Ophthalmol 2015;130:1-12.